Villarreal midfielder Santi Cazorla is set to make his first appearance for the Spanish national side in four years.
The 34-year old was recalled to the squad by Luis Enrique, and he start in their UEFA European Championships Qualifier against the Faroe Islands.
Enrique makes changes five from their last game, a 2-0 win in Malta, with Cazorla, Jesus Navas, Rodri, Isco and Iago Aspas all coming into the starting line up, in place of Juan Bernat, Saul Niguez, Marco Asensio, Sergio Canales and Rodrigo Moreno.
FAROE ISLANDS: Gestson, Sorensen, Gregersen, Faeroe, Davidsen, Hansson, Vatnsdal, B. Olsen, Vatnhamar, K. Olsen, Frederiksberg
SUBS: Bartalsstovu, Bjartalid, M. Olsen, Joensen, K. Hansen, Andreasen, Johannesen, Joensen, Baldvinsson, Eriksen, Egilsson
SPAIN: Kepa, Navas, Hermoso, Ramos, Gaya, Cazorla, Rodri, Roberto, Isco, Morata, Aspas
SUBS: De Gea. Lopez, Llorente, Parejo, Ruiz, Asensio, Alba, Carvajal, Busquets, Martinez, Oyarzabal